I just wanted to share a little information on this. We don't generally recommend deleting placeholders where possible as they will have been gathering information about your users - it would be for example like taking a card away from a pack reducing the number of combinations available to suit different situations;
When you create placeholders with Ezoic these are potential ad locations, so ads won't display in all these locations at once unless the system has gathered data from the user that demonstrates this is their individual preference.
So when you are are seeing ads you find intrusive or not aesthetic, other users may have a different opinion, but the beauty of the Ezoic system is that instead of picking a location that suits the majority, Ezoic can cater to both people who want an ad in that location and those who don't by leaving the placeholder in place.
Over time the system becomes wise to each user's preferences from the data collected and adapts ad combinations accordingly.
The reason you as a web owner may be seeing ads in locations you don't like is for example web owners often spend a long time on the site so the system may categorise you as having a high ad tolerance and show ads in locations you don't like, because your behavior on the site differs from how you'd browse as a user.